Ngā Pūrongo - He Tino Whai Hua te Tangohanga Rīwai Glabridin?

I. Kupu Whakataki

Kua whakanuia e te umanga tiaki kiri te kaha o te "whakamā"Glabridin"(i tangohia mai i te Glycyrrhiza glabra) nā te mea e hipa ana i te arbutin rangatira mā te 1164 ngā wā, ka whiwhi i te taitara "koura mā"! Engari he tino mīharo pērā i te tangi? Me pēhea e tutuki ai ēnei hua whakamiharo?

I te hurihanga o ngā wā, me te whakapaipai haere o ngā tiriti i ngā "waewae tahanga me ngā ringa tahanga," ko te kaupapa kōrero a te hunga e aroha ana ki te ataahua, i tua atu i te tiaki i te rā, ka huri ki te mā te kiri.

I roto i te ao tiaki kiri, he maha ngā momo kai whakama, tae atu ki te huaora C, te niacinamide, te arbutin, te hydroquinone, te waikawa kojic, te waikawa tranexamic, te glutathione, te waikawa ferulic, te phenethylresorcinol (377), me ētahi atu. Heoi anō, kua whakaoho te kai "glabridin" i te hiahia o te tini o ngā kaiwhaiwhai, ā, kua akiakihia he tūhuratanga hōhonu kia kitea ai tōna rongonui e tipu haere ana. Kia rukuhia ngā taipitopito!

Mā roto i tēnei tuhinga, ka aro atu mātou ki ngā kaupapa matua e whai ake nei:
(1) Nō hea te pūtake o Glabridin? He aha tōna hononga ki te "tangohanga Glycyrrhiza glabra"?
(2) He aha i whakanuia ai a "Glabridin" hei "koura whakama"?
(3) He aha ngā painga o "Glabridin"?
(4) Me pēhea te whakatutuki a Glabridin i ōna pānga mā?
(5) He pono rānei te kaha o te rīkiora e ai ki te kōrero?
(6) Ko ēhea ngā hua tiaki kiri kei roto ko Glabridin?

Nama 1 Te Whakakitenga i ngā Pūtake o "Glabridin"

Ko te Glabridin, he mema nō te whānau flavonoid rīkiora, i ahu mai i te tipu "Glycyrrhiza glabra." I tōku whenua, e waru ngā momo rīkiora matua, e toru ngā momo kei roto i te "Pharmacopoeia," arā, ko te rīkiora Ural, te rīkiora pupuhi, me te rīkiora glabra. Ko te Glycyrrhizin anake te mea e kitea ana i roto i te Glycyrrhiza glabra, koia te wāhanga isoflavone matua o te tipu.

Te tātai hanganga o te glycyrrhizin
I kitea tuatahitia te glycyrrhizin e te kamupene Hapanihi MARUZEN, ā, i tangohia mai i te Glycyrrhiza glabra, e whakamahia whānuitia ana hei tāpiringa i roto i ngā hua tiaki kiri mā puta noa i Hapani, Korea, me ngā waitohu tiaki kiri o te ao. Heoi, he mea nui kia mōhio ko te kai whakauru kua whakarārangihia i roto i ngā hua tiaki kiri e whakamahia ana e mātou, kāore pea i te "glycyrrhizin" engari ko te "tangohanga Glycyrrhiza." Ahakoa he matū kotahi te "Glycyrrhizin", tera pea kei roto i te "tangohanga Glycyrrhiza" ētahi atu wāhanga kāore anō kia tino wehea, kia purea hoki, ā, he mahi hokohoko pea hei whakanui i ngā āhuatanga "taiao" o te hua.

Nama 2 He aha i huaina ai te rīkiora he "Kaiwhakama Koura"?

He wāhanga onge, he wāhanga uaua hoki te tango i te Glycyrrhizin. Kāore e kitea ngāwari te nui o te Glycyrrhiza glabra. I te taha o te uaua o te tukanga tango, he iti iho i te 100 karamu te nui ka taea te whiwhi mai i te 1 tana o ngā kakau me ngā rau rīki hou. Nā tēnei onge te uara o tēnei wāhanga, ā, koia tētahi o ngā rauemi mata tino utu nui i roto i ngā hua tiaki kiri, he rite ki te koura. Ko te utu mō te 90% o ngā rauemi mata parakore o tēnei wāhanga ka piki ake ki te neke atu i te 200,000 yuan/kg.
I miharo ahau, nō reira i toro atu ahau ki te paetukutuku Aladdin ki te manatoko i ngā taipitopito. Kei te tukuna te raikoroihi parakore (te parakore ≥99%) i te utu whakatairanga o te 780 yuan/20mg, he rite ki te 39,000 yuan/g.
I roto i te wā poto, ka whiwhi au i te whakaute hou mō tēnei kai whakaitiiti. Nā tōna pānga whakamā e kore e taea te whakarite, kua tika ai te taitara "koura whakamā" me te "Kaiwhakamā Koura" rānei.

Nama 3 He aha te Mahi a Glabridin?

He maha ngā āhuatanga koiora o Glabridin. He kai whai hua, haumaru, ā, he pai hoki mō te whakama me te tango i ngā ira. Hei tāpiri, he pānga patu huakita, ārai mumura, ārai ārai mate, ārai koroheketanga, me te ārai i te hihi ultraviolet tōna. Ko tōna whai huatanga tino pai ki te whakama, ki te whakamārama, me te tango i ngā ira e tautokona ana e ngā raraunga whakamātautau, e whakaatu ana ko te pānga whakama o Glabridin he nui ake i te huaora C neke atu i te 230 ngā wā, te hydroquinone 16 ngā wā, me te arbutin rongonui he mea whakamiharo 1164 ngā wā.

Nama 4 He aha te tikanga whakama o te glabridin?

Ina pāngia te kiri e ngā hihi ultraviolet, ka puta ai te whakaputanga o ngā rauropi kore utu, ka whakaohokia ngā melanocytes ki te whakaputa tyrosinase. I raro i te mana o tēnei whākōkī, ka puta te melanin i roto i te kiri e te tyrosine, ka pōuri te kiri i te mea ka haria te melanin mai i te paparanga turanga ki te paparanga corneum.
Ko te kaupapa matua o tētahi kai whakama he whakauru ki te tukanga hanganga, te kawe rānei o te melanin. Ko te tikanga whakama a Glabridin e kapi ana i ngā āhuatanga e toru e whai ake nei:
(1) Te aukati i te mahi tyrosinase
He kaha te pānga aukati a Glabridin ki te mahi tyrosinase, ā, he mārama, he nui hoki ngā hua e puta mai ana. E whakaatu ana ngā whakatauira rorohiko ka taea e te glabridin te here pūmau ki te pokapū hohe o te tyrosinase mā roto i ngā hononga hauwai, ka ārai i te urunga mai o te rauemi mata mō te hanga melanin (tyrosine), ā, ka ārai i te hanga melanin. Ko tēnei huarahi, e mōhiotia ana ko te aukati whakataetae, he rite ki tētahi tohu aroha maia.

(2) Te pehi i te whakaputanga o ngā momo hāora tauhohe (antioxidant)
Mā te pānga o ngā hihi ultraviolet ka puta te whakaputanga o ngā momo hāora tauhohe (ngā rauropi kore utu), ka kino pea te kiriuhi phospholipid o te kiri, ka puta te whero me te tae kiri. Nō reira, e mōhiotia ana ka whai wāhi ngā momo hāora tauhohe ki te tae kiri, e whakaatu ana i te hiranga o te tiaki i te rā i roto i te tiaki kiri. Kua whakaatuhia e ngā rangahau whakamātautau he rite te kaha o te glabridin ki te tango i ngā rauropi kore utu ki te superoxide dismutase (SOD), he mahi antioxidant. Mā tēnei ka whakaiti i ngā āhuatanga e whai wāhi ana ki te pikinga o te mahi tyrosinase.

(3) Te aukati i te mumura
Whai muri i te kino o te kiri i ngā hihi ultraviolet, ka puta te whero me te tae kiri me te mumura, ka kaha ake te whakaputanga melanin me te pupuri tonu i tētahi huringa kino. Ka hangaia e ngā āhuatanga anti-inflammatory a Glabridin he taiao pai hei aukati i te hanganga melanin ki tētahi taumata, me te whakatairanga hoki i te whakatikatika i te kiri kua pakaru.

Nama 5 He Tino Kaha Ake Ake A Glabridin?

Kua whakanuia a Glabridin hei matū whai hua, ā, he pai hoki mō te taiao hei whakama me te tango i ngā ira, e whakamanamana ana ki tētahi tikanga whakama kua tautuhia pai, ā, he tino whai hua hoki. E whakaatu ana ngā raraunga whakamātautau he nui ake te pānga whakama i te arbutin "nui whakama" i te mano ngā wā (e ai ki ngā raraunga whakamātautau).
I whakahaerehia e ngā kairangahau tētahi tauira whakamātautau kararehe mā te whakamahi i te ika zebra hei aromatawai i te pānga aukati o te glabridin ki te melanin, e whakaatu ana i tētahi whakataurite nui ki te waikawa kojic me te bearberry.
Haunga ngā whakamātautau kararehe, e whakaatu ana hoki ngā hua haumanu i te pānga mā o te glabridin, ā, ka kitea ngā hua i roto i ngā wiki 4-8.
Ahakoa e kitea ana te whai huatanga o tēnei matū whakama, kāore i te whānui te whakamahinga o tēnei matū whakama ki ētahi atu. Ki taku whakaaro, ko te take matua kei roto i tōna "tūnga koura" i roto i te umanga—he utu nui! Heoi anō, whai muri i te whakamahinga o ngā hua tiaki kiri e kitea whānuitia ana, kei te piki haere te ia o te hunga e rapu ana i ngā hua kei roto tēnei matū "koura".

Nama 6 Ko ēhea Hua Tiaki Kiri kei roto ko Glabridin?

Whakakape: He rārangi noa iho tēnei, ehara i te tūtohutanga!
He matū tiaki kiri kaha te Glabridin e mōhiotia ana mō ōna āhuatanga whakamārama kiri. Ka kitea i roto i ngā momo hua tiaki kiri, tae atu ki ngā serum, ngā hinu, ngā hinu kiri, me ngā kopare. Heoi, ko ētahi hua motuhake kei roto pea te Glabridin, he mea nui kia mōhio ko te noho o te Glabridin i roto i ngā hua tiaki kiri ka rerekē pea, ā, he mea tika kia arotakehia ngā rārangi kai o ngā hua motuhake kia kitea ai kei roto.
(1) Rongoā Tinana mō te Kuini Raikoreti Aleble
Kei roto i te rārangi kai te "Glycyrrhiza glabra" hei kai tuarua (whai muri i te wai), me te glycerin, te sodium hyaluronate, te squalane, te ceramide, me ētahi atu wāhanga whakamakuku.
(2) Wai Whakaora Hua Māmā mō ngā Tamariki, he Wai Whakaora Hua Raikoreti
Ko ngā kai matua ko te tangohanga Glycyrrhiza glabra, te tangohanga rimurimu kua waikuratia, te arbutin, te tangohanga pakiaka Polygonum cuspidatum, te tangohanga pakiaka Scutellaria baicalensis, me ētahi atu.
(3) Kokoskin Snow Clock Essence Body Serum
Kei roto ko te 5% nicotinamide, 377, me te glabridin hei wāhanga matua.
(4) Kopare Kanohi Rīkoreti (Ngā Waitohu Rerekē)
He rerekē tēnei momo hua, ko ētahi he iti noa iho te nui, ā, e hokohokohia ana hei "glabragan" otaota.
(5) Raupapa Rīkoi Guyu

Nama 7 Te Whakamamae Wairua

(1) He mea tango mai i te raikoroihi te Glabridin i roto i ngā hua tiaki kiri?
He pātai tika te pātai mēnā i tangohia mai te Glabridin i roto i ngā hua tiaki kiri i te rīkiora. He rerekē te hanganga matū o te tango rīkiora, inā koa te glabridin, ā, he nui te utu mō te tukanga tango. Ka ara ake te pātai mēnā he pai ake te whakaaro ki te hanga matū hei huarahi kē atu mō te whiwhi glabridin. Ahakoa ka taea te whiwhi i ētahi matū, pērā i te artemisinin, mā te hanga katoa, he mea pea ka taea te hanga glabridin. Heoi, me whai whakaaro ki ngā pānga utu o te hanga matū ki te tango. Hei tāpiri, tera pea he āwangawanga mō te whakamahinga ā-tauira o te tapanga "tango Glycyrrhiza glabra" i roto i ngā rārangi kai o ngā hua tiaki kiri hei hanga i tētahi āhua hokohoko kai māori. He mea nui kia rukuhia ngā takenga mai me ngā tikanga whakaputa o ngā kai tiaki kiri kia mārama ai, kia pono ai hoki.

(2) Ka taea e au te pani tika i te raikōri parakore ki tōku mata kia mā ai tōku kiri?
Ko te whakautu he kāo nui! Ahakoa he mea whakamiharo te pānga mā o te glabridin, ko ōna āhuatanga e whakawhāiti ana i tana whakamahinga tika. He tata kore e wairewa te Glycyrrhizin i roto i te wai, ā, he ngoikore tōna kaha ki te uru ki te ārai kiri. Ko te whakauru i roto i ngā hua tiaki kiri me whai tukanga whakaputa me te whakarite pakari. Ki te kore he hanganga tika, he uaua ki te whakatutuki i te hua e hiahiatia ana. Heoi, kua arahina e te rangahau pūtaiao te whanaketanga o ngā whakaritenga ā-papa i roto i te ahua o ngā liposomes, e whakarei ake ana i te mimiti me te whakamahinga o te glabridin mā roto i te kiri.

ngā tohutoro:
[1] Pigmentation: dyschromia[M]. Thierry Passeron raua ko Jean-Paul Ortonne, 2010.
[2] J. Chen et al. / Spectrochimica Acta Wāhanga A: Te Tirotiro Irahiko me te Irahiko Koiora 168 (2016) 111–117