Konupūmā Methyltetrahydrofolate Parakore（5MTHF-Ca)
Ko te Konupūmā Methyltetrahydrofolate Parakore (5-MTHF-Ca) he momo folate e tino wātea ana i roto i te koiora, ā, ka taea te whakamahi ngāwari e te tinana. He tote konupūmā o te methyltetrahydrofolate, koinei te momo folate hohe i roto i te tinana. Ko te Folate he huaora B nui e whai wāhi nui ana ki ngā tukanga pūtau, tae atu ki te hanga DNA, te hanga pūtau toto whero, me te mahi a te pūnaha io.
He maha ngā wā ka whakamahia te MTHF-Ca hei tāpiringa kai hei tautoko i ngā taumata folate i roto i ngā tāngata e uaua ana ki te whakapūngao, ki te mimiti rānei i te āhua hangai o te waikawa folic e kitea ana i roto i ngā kai me ngā tāpiringa kua whakakahangia. He tino whai hua mō ngā tāngata he rerekētanga ira kei a rātou ka whakararu i te pākia o te folate.
Mā te tāpiritanga o te MTHF-Ca ka āwhina i te hauora me te oranga whānui, inā koa i ngā wāhanga pēnei i te hauora o te ngākau, te whanaketanga o te ngongo io i te wā e hapu ana, te mahi hinengaro, me te whakahaere i te wairua. He mea nui kia mōhiotia me whakamahi te MTHF-Ca i raro i te aratohu a te tohunga hauora, inā koa mō ngā tāngata whai mate hauora motuhake, mō te hunga rānei e tango ana i ētahi rongoā.
| Ingoa hua： | Konupūmā L-5-Methyltetrahydrofolate |
| Ngā kupu taurite： | 6S-5-Methyltetrahydrofolate konupūmā; Konupūmā L-5-Methyltetrahydrofolate; Konupūmā Levomefolate |
| Tātai ngota: | C20H23CaN7O6 |
| Taumaha ngota: | 497.52 |
| Nama CAS: | 151533-22-1 |
| Ihirangi: | ≥ 95.00% mā te HPLC |
| Āhua: | Paura tioata mā ki te kōwhai mārama |
| Whenua taketake: | Haina |
| Mōkihi: | 20kg/pahu |
| Te roa o te wā e pupuri ana: | 24 marama |
| Rokiroki: | Puritia ki te wāhi hauhautanga, maroke hoki. |
| Ngā taonga | Ngā Whakatakotoranga | Ngā Hua |
| Āhua | Paura mā, paura mā-parauri rānei | Whakaū |
| Te tautuhi | Pai | Whakaū |
| Konupūmā | 7.0%-8.5% | 8.4% |
| D-5-Methylfolate | ≤1.0 | Kāore i kitea |
| Ngā toenga i te mura | ≤0.5% | 0.01% |
| Wai | ≤17.0% | 13.5% |
| Whakamātautau (HPLC) | 95.0%-102.0% | 99.5% |
| Pungarehu | ≤0.1% | 0.05% |
| Metara Taumaha | ≤20 ppm | Whakaū |
| Tapeke o ngā Pereti | ≤1000cfu/g | Tohunga |
| Rewena me te Pokepokea | ≤100cfu/g | Tohunga |
| E.coil | Kino | Kino |
| Salmonella | Kino | Kino |
Teitei o te bioavailability:He momo folate tino wātea te MTHF-Ca i roto i te tinana, arā, he ngāwari te mimiti me te whakamahi e te tinana. He mea nui tēnei nā te mea ka uaua pea ki ētahi tāngata te huri i te waikawa folic hangai ki tōna āhua hohe.
Te momo hohe o te folate:Ko te MTHF-Ca te momo hohe o te folate, e mōhiotia ana ko te methyltetrahydrofolate. Ka whakamahia ngāwaritia tēnei momo e te tinana, ā, kāore e hiahiatia he tukanga hurihanga tāpiri.
Tote Konupūmā:He tote konupūmā te MTHF-Ca, arā, ka herea ki te konupūmā. Mā tēnei ka puta he painga tāpiri o te tāpiringa konupūmā me te tautoko folate. He mea nui te konupūmā mō te hauora o te wheua, te mahi uaua, te tuku io, me ētahi atu mahi tinana.
He pai mō ngā tāngata whai rerekētanga ira motuhake:He tino whai hua te MTHF-Ca mō ngā tāngata whai rerekētanga ira ka pā kino ki te pākia o te waikawa folic. Ka pā pea ēnei rerekētanga ira ki te kaha o te tinana ki te huri i te waikawa folic ki tōna āhua hohe, ā, me tāpiri atu ki te waikawa folic hohe.
E tautoko ana i ngā āhuatanga hauora maha:Ka taea e te tāpiringa MTHF-Ca te tautoko i te hauora me te oranga whānui. He tino whai hua mō te hauora o te ngākau, te whanaketanga o te ngongo io i te wā e hapu ana, te mahi hinengaro, me te whakahaere i te wairua.
He maha ngā painga hauora o te Konupūmā Methyltetrahydrofolate Parakore (MTHF-Ca):
Tautoko i te pākia o te folate:He momo folate tino wātea-koiora, he kaha hoki te MTHF-Ca. Ka āwhina i te tautoko i te pākia o te folate e te tinana, he mea nui mō te hanganga DNA, te hanga toto whero, me te mahi whānui o te pūtau.
Hauora ngākau:He mea nui ngā taumata folate e tika ana mō te hauora o te ngākau me te ngākau. Ka taea e te tāpiringa MTHF-Ca te āwhina ki te whakaiti i ngā taumata o te homocysteine, he waikawa amino, ina teitei ake, ka hono atu ki te pikinga o te mōrearea o te mate ngākau me te ngākau.
Tautoko mō te haputanga:He mea nui te MTHF-Ca i te wā e hapu ana, nā te mea ka āwhina i te ārai i ngā hapa ngongo io i roto i te whanaketanga o te kukune. E taunakihia ana kia whakarite kia rawaka ngā taumata folate a ngā wāhine e hapu ana, inā koa i ngā wā tōmua o te haputanga.
Te whakahaere i te wairua:He mea nui te mahi a te Folate i roto i te hanga neurotransmitter. Mā te nui o te folate ka tautoko i te hanga o te serotonin, dopamine, me te norepinephrine, he mea nui ēnei mō te whakahaere i te wairua. Tērā pea he pai te tāpiringa MTHF-Ca mō te hunga whai mate wairua, pērā i te pouri.
Te mahi hinengaro:He mea nui te Folate mō te mahi hinengaro me te hauora o te roro. Tērā pea ka tautoko te tāpiringa MTHF-Ca i te mahara, te arotahi, me te mahi hinengaro whānui, inā koa mō ngā kaumātua.
Tautoko kai:He pai te tāpiritanga MTHF-Ca mō ngā tāngata whai rerekētanga ira e pā ana ki te pākia o te folate. Tērā pea ka uaua ki ēnei tāngata te huri i te waikawa folic hangai ki tōna āhua hohe. Ka whakaratohia tika e te MTHF-Ca te āhua hohe o te folate, me te karo i ngā take hurihanga.
Ngā kai matūkai me ngā tāpiringa kai:E whakamahia whānuitia ana te MTHF-Ca hei wāhanga matua o ngā tāpiringa kai me ngā rongoā nutraceutical. He momo folate tino wātea-koiora tōna, ā, he maha ngā painga hauora e tukuna ana, e ai ki te kōrero i mua ake nei.
Te whakapakari i te kai me te inu:Ka taea te whakauru i te MTHF-Ca ki roto i ngā hua kai me ngā inu hei whakapakari i a rātou ki te folate. He mea nui rawa tēnei mō ngā hua e aro ana ki ngā taupori he ngoikore te folate, he nui ake rānei ngā hiahia mō te folate, pērā i ngā wāhine hāpu, i ngā tāngata rānei he mate hauora tō rātou.
Ngā whakatakotoranga rongoā:Ka taea te whakamahi i te MTHF-Ca i roto i ngā whakatakotoranga rongoā hei whakauru hohe. Ka taea te whakamahi i roto i ngā rongoā e aro ana ki ngā āhuatanga motuhake e pā ana ki te korenga o te folate, te ngoikore rānei o te pākia o te folate, pērā i te anemia, i ētahi mate ira rānei.
Te tiaki whaiaro me ngā mea whakapaipai:I ētahi wā ka whakaurua te MTHF-Ca ki roto i ngā hua tiaki whaiaro me ngā mea whakapaipai nā te mea he pai pea mō te hauora o te kiri. Kei roto te folate i ngā tukanga pūtau maha o te kiri, ā, ka whai wāhi pea ki tōna hauora me tōna āhua whānui.
Kai kararehe:Ka taea hoki te whakauru i te MTHF-Ca ki roto i te whāngai kararehe hei tāpiri i te folate ki ngā kararehe. He mea nui tēnei mō ngā ahumahi kararehe me te heihei, ina koa he mea nui te whakarite i te kai e tika ana mō te tipu me te hauora pai.
E whakaatu ana ēnei mara tono i te maha o ngā whakamahinga o te MTHF-Ca me tōna whakamahinga pea i roto i ngā momo ahumahi hei aro atu ki ngā āwangawanga hauora e pā ana ki te folate me ngā matea kai. Heoi, he mea nui kia whai i ngā aratohu horopeta tika me te kōrero ki ngā tohunga ina whakauruhia te MTHF-Ca ki roto i tētahi hua, i tētahi hanganga rānei.
Te pūtake o ngā rauemi mata:Ka tīmata te tukanga mā te kimi rauemi mata kounga teitei. Ko ngā rauemi mata matua e hiahiatia ana mō te hanga MTHF-Ca ko te waikawa folic me ngā tote konupūmā.
Te hurihanga o te waikawa folic ki te 5,10-Methylenetetrahydrofolate (5,10-MTHF):Ka hurihia te waikawa folic ki te 5,10-MTHF mā te tukanga whakaiti. Ko te tikanga o tēnei mahi ko te whakamahi i ngā matū whakaiti pēnei i te konutai borohydride, i ētahi atu whakakorikori rānei e tika ana.
Te tahuritanga o te 5,10-MTHF ki te MTHF-Ca:Ka tauhohehia anō te 5,10-MTHF ki tētahi tote konupūmā e tika ana, pērā i te konupūmā hauwaiora, te konupūmā kāponāte rānei, hei hanga i te Methyltetrahydrofolate Calcium (MTHF-Ca). Kei roto i tēnei tukanga te whakaranu i ngā matū tauhohe me te tuku i a rātou kia tauhohe i raro i ngā āhuatanga whakahaeretia, tae atu ki te pāmahana, te pH, me te wā tauhohe.
Te purenga me te tātari:I muri i te tauhohenga, ka pāngia te otinga MTHF-Ca e ngā tukanga purenga pērā i te tātari, te centrifugation, me ētahi atu tikanga wehewehe hei tango i ngā paru me ngā hua taha i puta pea i te wā o te tauhohenga.
Te whakamaroke me te whakapakeke:Kātahi ka tukatukahia anō te otinga MTHF-Ca kua purea hei tango i te makuku nui, hei whakapakeke hoki i te hua whakamutunga. Ka taea tēnei mā roto i ngā tikanga pēnei i te whakamaroke rehu, te whakamaroke tio rānei, i runga i te āhua o te hua e hiahiatia ana.
Te whakahaere kounga me te whakamātautau:Ka tukuna te hua MTHF-Ca whakamutunga ki raro i ngā tikanga whakahaere kounga pakari hei whakarite i tōna parakore, tōna pumau, me te piri ki ngā paerewa kounga kua tohua. Tērā pea kei roto i tēnei ko te whakamātautau mō ngā poke, te kaha, me ētahi atu tawhā e tika ana.
Te tākai me te rokiroki:Ka tākaihia te MTHF-Ca ki roto i ngā ipu e tika ana, kia tika ai te tapanga me ngā tikanga rokiroki kia mau tonu ai tōna āhua me tōna pumau. I te nuinga o te wā ka rongoatia ki te wāhi maroke, hauhautanga, kia matara atu i te rā tika.
Rokiroki: Puritia ki te wāhi hauhautanga, maroke, me te ma, Āraia mai i te makuku me te mārama tika.
Mōkihi papatipu: 25kg/pahu.
Wā Arataki: 7 ngā rā i muri i tō ota.
Te roa o te whakamahinga: 2 tau.
Tuhipoka: Ka taea hoki te whakatutuki i ngā whakaritenga kua whakaritea.
20kg/pēke 500kg/pallet
Tākai whakapakaritia
Haumarutanga logistics
Tere
I raro i te 100kg, 3-5 Ngā Rā
He ratonga tatau ki te tatau, he ngāwari ki te tiki taonga
Mā te Moana
Neke atu i te 300kg, Tata ki te 30 ngā rā
E hiahiatia ana he kaihoko whakaaetanga ngaio mō ngā ratonga tauranga ki tauranga
Mā runga Rererangi
100kg-1000kg, 5-7 rā
E hiahiatia ana he kaihoko ratonga whakawhiti ngaio mō ngā taunga rererangi ki te taunga rererangi
Konupūmā Methyltetrahydrofolate Parakore（5-MTHF-Ca)kua whakamanahia ki te tiwhikete ISO, tiwhikete HALAL, me te tiwhikete KOSHER.
Ko te rerekētanga i waenga i te whakatupuranga tuawhā o te waikawa folic (5-MTHF) me te waikawa folic tuku iho kei roto i tō rāua hanganga matū me te waatea o te tinana.
Hanganga matū:Ko te waikawa folic tuku iho he momo folate hangai me whai i ngā mahi hurihanga maha i roto i te tinana i mua i te whakamahinga. I tētahi atu taha, ko te waikawa folic o te whakatupuranga tuawhā, e mōhiotia ana ko te 5-MTHF, ko te Methyltetrahydrofolate rānei, ko te momo folate hohe, wātea-koiora kāore e hiahiatia he hurihanga.
Te wātea o te koiora:Me huri te waikawa folic tuku iho ki tōna āhua hohe, 5-MTHF, mā roto i ngā tauhohenga whākōkī i roto i te tinana. He rerekē tēnei tukanga hurihanga i waenga i ngā tāngata takitahi, ā, ka pāngia e ngā rerekētanga ira, e ētahi atu āhuatanga rānei. He rerekē, kua noho kē te 5-MTHF i roto i tōna āhua hohe, ā, e wātea ana mō te tango me te whakamahi a ngā pūtau.
Te mimiti me te whakamahinga:Ka mimiti te waikawa folic tuku iho i roto i te whekau iti, me huri ki te āhua hohe e te whākōkī dihydrofolate reductase (DHFR). Heoi, kāore tēnei tukanga hurihanga i te tino whai hua mō ētahi tāngata, ā, ka iti ake te wātea o te koiora. Ko te 5-MTHF, te āhua hohe, ka mimiti wawetia, ka whakamahia hoki e te tinana, ā, ka karo i te tukanga hurihanga. Nā tēnei ka waiho hei momo pai mō ngā tāngata he rerekētanga ira, he āhuatanga rānei e pā ana ki te pākia o te folate.
Te hauora mō ētahi tāngata:Nā te rerekētanga o te mimiti me te whakamahinga, e kiia ana he pai ake te 5-MTHF mō ngā tāngata whai rerekētanga ira, pērā i ngā whakarerekētanga ira MTHFR, ka taea te whakararu i te huringa o te waikawa folic ki tōna āhua hohe. Mō ēnei tāngata, mā te whakamahi tika i te 5-MTHF ka taea te whakarite i ngā taumata folate tika i roto i te tinana me te tautoko i ngā mahi koiora.
Tāpiritanga:Ko te waikawa folic tuku iho e kitea whānuitia ana i roto i ngā tāpiringa, ngā kai whakakaha, me ngā kai tukatuka, nā te mea he pumau ake, he iti ake hoki te utu ki te whakaputa. Heoi, kei te piki haere te wātea o ngā tāpiringa 5-MTHF e whakarato tika ana i te āhua hohe, he mea whai hua mō te hunga e uaua ana ki te huri i te waikawa folic.
He onge noa iho, he ngawari hoki ngā pānga taha o te waikawa folic o te whakatupuranga tuawhā (5-MTHF), engari he mea nui kia mōhio ki ngā pānga ka pā mai:
Ngā tauhohenga mate pāwera:Pērā i ngā tāpiringa me ngā rongoā katoa, ka taea ngā mate pāwera. Ko ngā tohumate pea ko te ponana, te mākati, te pupuhi, te whanoke, te uaua rānei ki te manawa. Ki te pāngia koe e tētahi o ēnei tohumate, rapua tonutia te awhina hauora.
Ngā raruraru nakunaku:Tērā pea ka pāngia ētahi tāngata e ngā mamae o te puku, pērā i te whakapairuaki, te pupuhi, te hau, te mate korere rānei. He wā poto noa iho ēnei tohu, ā, ka memeha haere i te wā e taunga ai te tinana ki te tāpiringa.
Ngā taunekeneke me ngā rongoā:Tērā pea ka taunekeneke te 5-MTHF me ētahi rongoā, tae atu ki ngā rongoā e whakamahia ana hei rongoā matepukupuku, ngā rongoā ārai mate, te methotrexate, me ētahi paturopi. He mea nui kia kōrero koe ki tō kaiwhakarato hauora mēnā kei te tango koe i tētahi rongoā kia kore ai he taunekeneke pea.
Te nui rawa o te horopeta, te nui rawa rānei o te folate:Ahakoa he onge, ko te nui rawa o te folate (tae atu ki te 5-MTHF) ka arahi pea ki te nui o te folate i roto i te toto. Tērā pea ka hunaia ngā tohu o te korenga o te huaora B12, ā, ka pā ki te tātaritanga me te maimoatanga o ētahi mate. He mea nui kia whai i te horopeta kua tūtohutia, me te kōrero ki tētahi tohunga hauora hei ārahi.
Ētahi atu whakaaro:Me kōrero ngā wāhine hapu, me te hunga rānei e whakaaro ana kia hapu ki tā rātou kaiwhakarato hauora i mua i te tango i ngā horopeta teitei ake o te 5-MTHF, nā te mea ka taea e te nui o te kai folate te huna i ngā tohu o te korenga o te huaora B12, he mea nui tēnei mō te whanaketanga o te ngongo io i roto i te kukune.
Pērā i ngā tāpiringa kai, rongoā rānei, me kōrero tahi me te kaiwhakarato hauora mō te whakamahinga o te waikawa folic o te whakatupuranga tuawhā (5-MTHF), inā koa mēnā he mate hauora tōu, kei te tango rongoā rānei koe. Ka taea e rātou te tuku tohutohu takitahi i runga i ō hiahia me te āwhina ki te aroturuki i ngā pānga taha pea.
Ko te waikawa folic o te whakatupuranga tuawhā, e mōhiotia ana ko te 5-methyltetrahydrofolate (5-MTHF), he momo folate hohe koiora e ngāwari ake ana te mimiti me te whakamahi e te tinana ki te whakataurite ki te tāpiringa waikawa folic tuku iho. Anei ētahi rangahau pūtaiao e tautoko ana i tōna whai huatanga:
Te pikinga ake o te bioavailability:Kua whakaatuhia he nui ake te wātea o te 5-MTHF i te waikawa folic. I roto i tētahi rangahau i whakaputaina i roto i te American Journal of Clinical Nutrition, i whakaritea te wātea o te waikawa folic me te 5-MTHF i roto i ngā wāhine hauora. I kitea he tere ake te mimiti o te 5-MTHF, ā, i piki ake ai ngā taumata folate i roto i ngā toto toto whero.
Te whakapai ake i te tūnga folate:He maha ngā rangahau kua whakaatu mai ka taea e te tāpiringa 5-MTHF te whakanui ake i ngā taumata folate toto. I roto i tētahi whakamātautau matapōkeretia i whakaputaina i roto i te Journal of Nutrition, i whakaritea e ngā kairangahau ngā pānga o te 5-MTHF me te tāpiringa waikawa folic ki te tūnga folate i roto i ngā wāhine hauora. I kitea e rātou he nui ake te whai huatanga o te 5-MTHF ki te whakanui ake i ngā taumata folate toto whero i te waikawa folic.
Te whakanui ake i te pākia o te waikawa folic:Kua whakaaturia te kaha o te 5-MTHF ki te karo i ngā mahi whākōkī e hiahiatia ana mō te whakahohenga o te waikawa folic, ā, ka whai wāhi tika ki te pākia o te waikawa folic pūtau. I whakaatuhia i roto i tētahi rangahau i whakaputaina i roto i te Journal of Nutrition and Metabolism, ko te tāpiringa 5-MTHF i whakapai ake i te pākia o te waikawa folic pūtau i roto i ngā tāngata he rerekētanga ira kei roto i ngā whākōkī e uru ana ki te whakahohenga o te waikawa folic.
Ngā taumata homocysteine kua whakaitihia:Ko te nui haere o te homocysteine, he waikawa amino i roto i te toto, e pā ana ki te pikinga ake o te mōrearea o ngā mate pūnaha toto. Kua whakaatuhia e ngā rangahau ka taea e te tāpiringa 5-MTHF te whakaiti i ngā taumata homocysteine. I tātarihia e tētahi tātaritanga-maha i whakaputaina i roto i te Journal of the American College of Nutrition ngā whakamātautau whakahaere matapōkere e 29, ā, i whakatauhia he nui ake te whai huatanga o te tāpiringa 5-MTHF i te waikawa folic ki te whakaiti i ngā taumata homocysteine.
He mea nui kia mōhiotia he rerekē pea ngā urupare a te tangata takitahi ki te tāpiringa, ā, ko te whai huatanga o te 5-MTHF ka whakawhirinaki pea ki ngā āhuatanga pēnei i ngā rerekētanga ira o ngā whākōkī pākia o te folate me te kai whānui e kainga ana. He mea pai tonu kia kōrero ki tētahi kaiwhakarato hauora mō ngā tohutohu whaiaro e pā ana ki te tāpiringa, me te matapaki i ngā āwangawanga hauora, i ngā āhuatanga rānei.
