Waikōroiti Raikorini
Ko te Lycorine hydrochloride he paura mā ki te mā-parauri i ahu mai i te alkaloid lycorine, e kitea ana i roto i ngā tipu o Lycoris radiata (L'Her.), ā, nō te whānau Amaryllidaceae. He maha ngā pānga rongoā pea o te Lycorine hydrochloride, tae atu ki te ārai i te pukupuku, te ārai i te mate pukupuku, te ārai i te HCV, te ārai i te mumura, te ārai i te huakita, te ārai i te huaketo, te ārai i te angiogenesis, me ngā āhuatanga ārai i te malaria. Ka wairewa i roto i te wai, te DMSO, me te etanoru. Ko tōna hanganga matū e tohuhia ana e te anga steroidal matatini me te reka kawa me ngā rōpū mahi maha, tae atu ki ngā rōpū hydroxyl me te amino, e whai wāhi ana ki ana mahi koiora.
| Ingoa hua | Raikorini hauwaiora CAS:2188-68-3 | ||
| Pūtake Tipu | Lycoris | ||
| Āhua rokiroki | Penapena ki te hiri i te pāmahana rūma | Te rā o te pūrongo | 2024.08.24 |
| Taonga | Paerewa | Hua |
| Te parakore（HPLC） | Lycorine hydrochloride≥98% | 99.7% |
| Āhua | Paura mā-parauri | Ngā ritenga |
| Āhuatanga ā-tinanaics | ||
| Rahi-matūriki | NLT100% 80Matapihi | Ngā ritenga |
| Ngaronga i te whakamaroketanga | ≤1.0% | 1.8% |
| Taumaha whakarewa | ||
| Ngā konganuku katoa | ≤10.0ppm | Ngā ritenga |
| Ārahi | ≤2.0ppm | Ngā ritenga |
| Merekurai | ≤1.0ppm | Ngā ritenga |
| Kāmiuma | ≤0.5ppm | Ngā ritenga |
| Ngā rauropi iti | ||
| Te tapeke o ngā huakita | ≤1000cfu/g | Ngā ritenga |
| rewena | ≤100cfu/g | Ngā ritenga |
| Escherichia coli | Kāore i whakaurua | Kāore i kitea |
| Salmonella | Kāore i whakaurua | Kāore i kitea |
| Staphylococcus | Kāore i whakaurua | Kāore i kitea |
| Ngā Whakatau | Tohunga | |
Ngā Āhuatanga:
(1) Teitei o te Parakore:Ka tukatukahia ā mātou hua me te tino tupato kia tino parakore, he mea nui tēnei mō tōna whai huatanga me tōna haumaru i roto i ngā momo mahi.
(2) Ngā Āhuatanga Ārai Matepukupuku:Kua whakaatuhia e ia he pānga nui ki te ārai matepukupuku ki ngā momo matepukupuku maha, i roto i te vitro me te in vivo, mā roto i ngā tikanga pēnei i te aukati i te huringa pūtau, te whakaoho i te apoptosis, me te aukati i te angiogenesis.
(3) Mahi Whāia-maha:E whakaponohia ana ka taunekeneke te Lycorine hydrochloride me ngā whāinga ngota maha, ka tuku i te whai huatanga whānui ki ngā pūtau matepukupuku.
(4) Paitini iti:He iti te paitini o tēnei mea ki ngā pūtau noa, he mea nui tēnei hei whakamahi māna hei rongoā.
(5) Kōtaha Rongoā:Kua rangahaua te hua mō ōna āhuatanga pharmacokinetic, e whakaatu ana i te tere o te mimiti me te tere o te tango atu i te toto, he mea nui tēnei mō te horopeta me te whakamahere maimoatanga.
(6) Ngā Pānga Mahi Tahi:Kua whakaatuhia e te Lycorine hydrochloride he pānga pai ake ina whakamahia ngātahi me ētahi atu rongoā, ā, he mea whai hua tēnei ki te wikitoria i te ātete ki te rongoā me te whakapai ake i ngā putanga maimoatanga.
(7) Tautokona e te Rangahau:E tautokona ana te hua e te rangahau whānui, e whakarato ana i te turanga pakari mō tōna whakamahinga i roto i te whanaketanga rongoā me ngā tono haumanu.
(8) Te Whakapūmau Kounga:Kua whakatinanahia ngā mahi whakahaere kounga pakari puta noa i te tukanga whakaputa hei whakarite i te ōritetanga me te pono o te hua.
(9) Ngā Whakamahinga Maha:He pai mō te whakamahi i roto i te rangahau me te whanaketanga mō ngā tono rongoā, tae atu ki te kimi rongoā me te whakawhanaketanga maimoatanga mate pukupuku.
(10) Te Whakatutukitanga:I hangaia kia rite ki ngā paerewa GMP hei whakarite i te haumaru me te whai huatanga o te hua.
(1) Te umanga rongoā:E whakamahia ana te Lycorine hydrochloride hei whakawhanake i ngā rongoā ārai huaketo me te rongoā ārai matepukupuku.
(2) Te umanga hangarau koiora:E whakamahia ana i roto i te rangahau me te whakawhanake i ngā rongoā hou me ngā rongoā whai hua.
(3) Rangahau mō ngā hua taiao:E rangahauhia ana te Lycorine hydrochloride mō ōna painga hauora me ōna āhuatanga rongoā.
(4) Ahumahi matū:Ka taea te whakamahi hei takawaenga matū i roto i te hanganga o ētahi atu pūhui.
(5) Ahumahi ahuwhenua:Kua rangahaua te kaha o te lycorine hydrochloride hei patu pepeke taiao me te whakahaere tipu tipu.
Ko te tukanga tango o te lycorine hydrochloride e whai ake nei ngā mahi matua hei whakarite i te parakore o te whakarewa me te whakapai ake i te tere whakaora:
(1) Te whiriwhiri rauemi mata me te maimoatanga i mua:Kōwhiria ngā rauemi mata o te tipu Amaryllidaceae e tika ana, pērā i ngā pūmua Amaryllis, ka horoia, ka whakamaroke, ka kuru kia tino parakore ai ngā rauemi mata, ā, ka whakatakoto i te turanga mō te tangohanga i muri mai.
(2)Te maimoatanga o mua o te whākōkī hiato:Whakamahia ngā whākōkī matatini (pēnei i te cellulase me te pectinase) hei tukatuka i ngā rauemi mata kua kuruhia hei wawahi i ngā pakitara pūtau tipu me te whakapai ake i te whai huatanga o te tangohanga i muri mai.
(3)Te tātānga waikawa hauwai waimeha:Whakaranua ngā rauemi mata kua tukatukahia ki te otinga waikawa hauwaiwaiwai hei tango i te lycorine. Mā te whakamahi i te waikawa hauwaiwaiwai ka āwhina i te whakanui ake i te wairewatanga o te lycorine, ā, ka pai ake te whai huatanga o te tango.
(4)Te tangohanga āwhina-orohiko:Mā te whakamahi i te hangarau tango-āwhina ultrasonic ka taea te whakatere i te tukanga memeha o te lycorine i roto i te whakarewa me te whakapai ake i te pai o te tango me te ma.
(5)Te tango i te kōroporomu:Ka whakamahia ngā whakarewa waro pērā i te chloroform hei tango, ā, ka whakawhitia te lycorine mai i te wāhanga wai ki te wāhanga waro hei purenga anō i te matū e hiahiatia ana.
(6)Te whakaora i te whakarewa:I muri i te tukanga tango, ka whakahokia mai te whakarewa mā te mimiti, mā te whakangao rānei hei whakaiti i te whakamahinga o te whakarewa, hei whakapai ake hoki i te ōhanga.
(7)Te purenga me te whakamaroke:Mā ngā mahi purenga me te whakamaroke e tika ana, ka puta te paura lycorine hydrochloride parakore.
I roto i te tukanga tango katoa, ko te whakahaere i te kōwhiringa whakarewa, ngā tikanga tango (pēnei i te uara pH, te pāmahana, me te wā), me ngā mahi purenga i muri mai ko te mea nui hei whakarite i te parakore o te whakarewa me te whakapai ake i te tere whakaora. Ko te whakamahinga o ngā taputapu tango me te purenga hou, pēnei i ngā taputapu tango ultrasonic me ngā pūnaha chromatography wai mahi-teitei (HPLC), ka āwhina hoki ki te whakapai ake i te whai huatanga o te tango me te kounga o te hua.
Rokiroki: Puritia ki te wāhi hauhautanga, maroke, me te ma, Āraia mai i te makuku me te mārama tika.
Mōkihi papatipu: 25kg/pahu.
Wā Arataki: 7 ngā rā i muri i tō ota.
Te roa o te whakamahinga: 2 tau.
Tuhipoka: Ka taea hoki te whakatutuki i ngā whakaritenga kua whakaritea.
Tere
I raro i te 100kg, 3-5 Ngā Rā
He ratonga tatau ki te tatau, he ngāwari ki te tiki taonga
Mā te Moana
Neke atu i te 300kg, Tata ki te 30 ngā rā
E hiahiatia ana he kaihoko whakaaetanga ngaio mō ngā ratonga tauranga ki tauranga
Mā runga Rererangi
100kg-1000kg, 5-7 rā
E hiahiatia ana he kaihoko ratonga whakawhiti ngaio mō ngā taunga rererangi ki te taunga rererangi
Kua whiwhi a Bioway Organic i ngā tiwhikete USDA me EU organic, BRC, ISO, HALAL, KOSHER, me te HACCP.
He alkaloid tūturu te lycorine e kitea ana i roto i ētahi tipu, inā koa i roto i te whānau Amaryllidaceae. Anei ētahi tipu e mōhiotia ana kei roto te lycorine:
Lycoris radiata(e mōhiotia ana ko te rengarenga pūngāwerewere whero, ko te manjushage rānei) he otaota rongoā tuku iho Hainamana kei roto ko te lycorine.
Leucojum aestivum(te hukarere raumati), e mōhiotia ana hoki kei roto he lycorine.
Ungernia sewertzowiiKo tētahi atu tipu nō te whānau Amaryllidaceae kua pūrongohia kei roto ko te lycorine.
Hippeastrum ranu (te rengarenga o te Īta)me ētahi atu tipu e pā ana ki te Amaryllidaceae he puna rongonui mō te lycorine.
He whānui te horapa o ēnei tipu ki ngā rohe pārūrū me ngā rohe pārūrū huri noa i te ao, ā, kua roa nei e whakamahia ana i roto i ngā rongoā tuku iho. Ko te noho mai o te lycorine i roto i ēnei tipu kua waiho hei kaupapa rangahau nā te mea he āhuatanga rongoā pea ōna, tae atu ki ōna pānga nui ki te ārai matepukupuku e whakaaturia ana i roto i ngā rangahau maha.
He alkaloid tūturu te lycorine me te whānuitanga o ngā pānga rongoā, tae atu ki tōna whakamahinga pea i roto i te rongoā mate pukupuku. Ahakoa kua whakaatuhia he hua pai i roto i ngā rangahau maha, kei reira ētahi pānga taha me ngā whakaaro e pā ana ki tōna whakamahinga:
Iti te Paitini: Ko te Lycorine me tōna tote hauwaiora he iti te paitini, he āhuatanga pai tēnei mō ngā mahi haumanu. Kua whakaatuhia he iti noa ngā pānga kino ki ngā pūtau tangata noa me ngā kiore hauora, e tohu ana i tētahi taumata o te whiriwhiri mō ngā pūtau matepukupuku i ngā kiko noa.
Ngā Pānga Puku Wā Poto: Kua kitea te whakapairuaki me te ruaki wā poto i muri i te werohanga o te lycorine hydrochloride ki raro i te kiri, ki roto rānei i te uaua, ā, ka memeha haere i roto i ngā haora 2.5 me te kore e pā ki te haumaru o ngā matū koiora, o te toto rānei.
Kāore he Whakararuraru i te Taunga Nekeneke: Kua whakaatuhia e ngā rangahau kāore ngā horopeta raupapa o te lycorine e pā ki te taunga nekeneke o ngā kiore, e ai ki te whakamātautau rotarod, e tohu ana kāore e arahi ki ngā pānga taha o te pūnaha io matua (CNS) e pā ana ki te whakahaere nekeneke.
Pānga ki te Mahi Nekeneke Tūroa: I te horopeta o te 30 mg/kg, kua kitea te ngoikore o te mahi nekeneke tūroa a te lycorine i roto i ngā kiore, e tohuhia ana e te hekenga o te whanonga whakatipu me te pikinga o te kore e nekeneke.
Te Whanoke me te Oranga Whānui: Kāore te horopeta o te 10 mg/kg o te lycorine i whakararu i ngā whanonga whānui me te oranga o ngā kiore, e tohu ana koinei pea te horopeta tino pai mō ngā aromatawai whai huatanga rongoā a meake nei.
Kāore he Pānga Kino Nui ki te Taumaha Tinana, ki te Tūnga Hauora rānei: Kāore i puta he pānga taha kitea ki te taumaha tinana, ki te tūnga hauora whānui rānei i roto i ngā tauira kiore he pukupuku i te wā i hoatu ai te lycorine me te lycorine hydrochloride.
He mea nui kia mōhiotia ahakoa kua whakaatuhia te kaha o te lycorine i roto i ngā rangahau i mua i te haumanu, kei te ngaro tonu ngā aromatawai paitini mō te wā roa. Me whai rangahau anō kia tino mārama ai ki tōna āhua haumaru, inā koa mō te whakamahinga mō te wā roa me ngā tautuhinga haumanu. Ka rerekē pea ngā pānga taha me te haumaru o te lycorine i runga i te horopeta, te tikanga whakahaere, me ngā āhuatanga takitahi o te tūroro. Me kōrero tonu ki tētahi tohunga hauora i mua i te whakaaro ki te whakamahi i tētahi tāpiringa hou, i tētahi maimoatanga hou rānei.
